HEPATOPROTECTIVE POTENTIAL OF SAFFLOWER OIL COMPARED TO COTTONSEED OIL

Toxic hepatitis is accompanied by profound hepatocellular damage and impairment of vital metabolic processes. One of the main markers of hepatocyte destruction is the elevation of cytolytic enzymes, particularly alanine aminotransferase (ALT) and aspartate aminotransferase (AST) [3,6]. Pharmacological hepatoprotectors are effective but often associated with side effects and limited accessibility in long-term use [1, 4]. Natural oils with bioactive components represent a promising alternative to restore liver function. Safflower oil has been noted for its hepatoprotective properties, but comparative studies with other vegetable oils remain insufficient [2, 5]. Clarifying these effects is important for integrating dietary oils into hepatology practice.