Mechanistic understanding and validation of large AI models with SemanticLens

Abstract Unlike human-engineered systems, such as aeroplanes, for which the role and dependencies of each component are well understood, the inner workings of artificial intelligence models remain largely opaque, which hinders verifiability and undermines trust. Current approaches to neural network interpretability, including input attribution methods, probe-based analysis and activation visualization techniques, typically provide limited insights about the role of individual components or require extensive manual interpretation that cannot scale with model complexity. This paper introduces SemanticLens, a universal explanation method for neural networks that maps hidden knowledge encoded by components (for example, individual neurons) into the semantically structured, multimodal space of a foundation model such as CLIP. In this space, unique operations become possible, including (1) textual searches to identify neurons encoding specific concepts, (2) systematic analysis and comparison of model representations, (3) automated labelling of neurons and explanation of their functional roles, and (4) audits to validate decision-making against requirements. Fully scalable and operating without human input, SemanticLens is shown to be effective for debugging and validation, summarizing model knowledge, aligning reasoning with expectations (for example, adherence to the ABCDE rule in melanoma classification) and detecting components tied to spurious correlations and their associated training data. By enabling component-level understanding and validation, the proposed approach helps mitigate the opacity that limits confidence in artificial intelligence systems compared to traditional engineered systems, enabling more reliable deployment in critical applications.

Institutions

Publication Details

Journal
Nature Machine Intelligence
Published
2025-08-14
DOI
https://doi.org/10.1038/s42256-025-01084-w
Citations
2
Primary Topic
Geochemistry and Geologic Mapping
Type
article
Field-Weighted Citation Impact
4.96

Funders

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article

Mechanistic understanding and validation of large AI models with SemanticLens

2 citations
Nature Machine Intelligence
Geochemistry and Geologic Mapping
4.96
article

Mechanistic understanding and validation of large AI models with SemanticLens

article en
2 citations

Abstract

Abstract Unlike human-engineered systems, such as aeroplanes, for which the role and dependencies of each component are well understood, the inner workings of artificial intelligence models remain largely opaque, which hinders verifiability and undermines trust. Current approaches to neural network interpretability, including input attribution methods, probe-based analysis and activation visualization techniques, typically provide limited insights about the role of individual components or require extensive manual interpretation that cannot scale with model complexity. This paper introduces SemanticLens, a universal explanation method for neural networks that maps hidden knowledge encoded by components (for example, individual neurons) into the semantically structured, multimodal space of a foundation model such as CLIP. In this space, unique operations become possible, including (1) textual searches to identify neurons encoding specific concepts, (2) systematic analysis and comparison of model representations, (3) automated labelling of neurons and explanation of their functional roles, and (4) audits to validate decision-making against requirements. Fully scalable and operating without human input, SemanticLens is shown to be effective for debugging and validation, summarizing model knowledge, aligning reasoning with expectations (for example, adherence to the ABCDE rule in melanoma classification) and detecting components tied to spurious correlations and their associated training data. By enabling component-level understanding and validation, the proposed approach helps mitigate the opacity that limits confidence in artificial intelligence systems compared to traditional engineered systems, enabling more reliable deployment in critical applications.

Nature Machine IntelligenceVol. 7(9)
Fraunhofer Institute for Telecommunications, Heinrich Hertz Institute (DE), Technological University Dublin (IE), Berlin Institute for the Foundations of Learning and Data (DE), Technische Universität Berlin (DE)
Fraunhofer-Gesellschaft
Peace, Justice and strong institutions
Openalex Percentile: Top 4%
Geochemistry and Geologic Mapping
4.96
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Mechanistic understanding and validation of large AI models with SemanticLens · Nature Machine Intelligence (2025) | TGRS Research Map | TGRS