Breast Hamartoma in Pregnancy: A Case Report

Background: Breast hamartomas are rare benign lesions composed of an abnormal mixture of glandular, fibrous and adipose tissues. They are typically seen in middle-aged women, with a peak incidence between 35 and 55 years and are uncommon in younger women or during pregnancy. The physiological changes of pregnancy-including lobuloalveolar proliferation, ductal enlargement and increased vascularity-can complicate the detection and evaluation of breast lesions. Case Presentation: We report the case of a 26-year-old woman in her second trimester of pregnancy who presented with an augmented painless right breast mass. Ultrasound demonstrated imaging features suggestive of a hamartoma or phyllodes tumor. Conservative management was undertaken throughout pregnancy, with careful monitoring. Following delivery, an excisional biopsy confirmed the diagnosis histologically. Conclusion: Although hamartomas are rare in pregnant women, they should be included in the differential diagnosis of breast masses detected during gestation. Imaging with ultrasound and MRI provides valuable diagnostic guidance. Conservative follow-up during pregnancy, with postpartum excision for histological confirmation, is a safe and effective strategy. Reporting such cases contributes to the clinical literature by providing guidance for the diagnosis and management of rare breast tumors during pregnancy.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-09-03
DOI
https://doi.org/10.5281/zenodo.17066884
Primary Topic
Geochemistry and Geologic Mapping
Type
article
Field-Weighted Citation Impact
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article

Breast Hamartoma in Pregnancy: A Case Report

Zenodo (CERN European Organization for Nuclear Research)
Geochemistry and Geologic Mapping
article

Breast Hamartoma in Pregnancy: A Case Report

article en

Abstract

Background: Breast hamartomas are rare benign lesions composed of an abnormal mixture of glandular, fibrous and adipose tissues. They are typically seen in middle-aged women, with a peak incidence between 35 and 55 years and are uncommon in younger women or during pregnancy. The physiological changes of pregnancy-including lobuloalveolar proliferation, ductal enlargement and increased vascularity-can complicate the detection and evaluation of breast lesions. Case Presentation: We report the case of a 26-year-old woman in her second trimester of pregnancy who presented with an augmented painless right breast mass. Ultrasound demonstrated imaging features suggestive of a hamartoma or phyllodes tumor. Conservative management was undertaken throughout pregnancy, with careful monitoring. Following delivery, an excisional biopsy confirmed the diagnosis histologically. Conclusion: Although hamartomas are rare in pregnant women, they should be included in the differential diagnosis of breast masses detected during gestation. Imaging with ultrasound and MRI provides valuable diagnostic guidance. Conservative follow-up during pregnancy, with postpartum excision for histological confirmation, is a safe and effective strategy. Reporting such cases contributes to the clinical literature by providing guidance for the diagnosis and management of rare breast tumors during pregnancy.

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 51%
Geochemistry and Geologic Mapping
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