Synthetic data generation for training healthcare NLP models without compromising privacy

The Natural Language Processing (NLP) models have been known to be highly promising in medical care, especially in clinical note summarization, prediction of diagnoses, as well as in classification of patient records. Nevertheless, medical text data is sensitive, which raises critical privacy issues and regulatory restrictions thus, hindering access to training data of high quality. Data generation via synthesis is an attractive alternative because it generates artificial dataset that replicates the statistical figures of real clinical narratives, but without ending up at identifying patient data. This article details the sophisticated approaches to the construction of synthetic medical data suitable in machine learning settings with NLP downstream tasks based on generative adversarial networks (GANs) and large language models (LLMs) and rule-based methods of anonymization augmentation. Various types of NLP models are trained on real and synthetic data and the researchers check the quality of their performance and find out how predictive and linguistically relevant privacy-preserving synthetic datasets can be. According to our findings, good-quality synthetic datasets can serve as a source of preserving privacy as well as training a reliable model that can be used to apply AI in medicine in a safer and scalable way.

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-05-05
DOI
https://doi.org/10.5281/zenodo.17062967
Primary Topic
Geochemistry and Geologic Mapping
Type
article
Field-Weighted Citation Impact
0.00
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article

Synthetic data generation for training healthcare NLP models without compromising privacy

Zenodo (CERN European Organization for Nuclear Research)
Geochemistry and Geologic Mapping
article

Synthetic data generation for training healthcare NLP models without compromising privacy

article en

Abstract

The Natural Language Processing (NLP) models have been known to be highly promising in medical care, especially in clinical note summarization, prediction of diagnoses, as well as in classification of patient records. Nevertheless, medical text data is sensitive, which raises critical privacy issues and regulatory restrictions thus, hindering access to training data of high quality. Data generation via synthesis is an attractive alternative because it generates artificial dataset that replicates the statistical figures of real clinical narratives, but without ending up at identifying patient data. This article details the sophisticated approaches to the construction of synthetic medical data suitable in machine learning settings with NLP downstream tasks based on generative adversarial networks (GANs) and large language models (LLMs) and rule-based methods of anonymization augmentation. Various types of NLP models are trained on real and synthetic data and the researchers check the quality of their performance and find out how predictive and linguistically relevant privacy-preserving synthetic datasets can be. According to our findings, good-quality synthetic datasets can serve as a source of preserving privacy as well as training a reliable model that can be used to apply AI in medicine in a safer and scalable way.

Zenodo (CERN European Organization for Nuclear Research)
Quality Education
Openalex Percentile: Top 52%
Geochemistry and Geologic Mapping
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