Cracking the glass: a look into the mysterious post larval disease affecting aquaculture

Translucent Post-Larvae Disease (TPD), also known as Post-Larval Glass Disease (PLGD), poses a serious threat to shrimp aquaculture, particularly affecting Penaeus vannamei post-larvae. First identified in 2020 in China and Vietnam, it is caused by a virulent Vibrio parahaemolyticus strain (Vp-JS20200428004-2), distinct from AHPND, and often co-infected with Baishivirus. Symptoms include glassy transparency, empty guts, and lethargy. Diagnosis involves clinical signs, molecular tests, and VHVP-2 primers. The disease leads to economic loss and reduced exports. Effective control relies on early detection, improved biosecurity, and targeted treatment. PLGD highlights the urgent need for regional cooperation and sustainable management strategies.