Pancreatic Neuroendocrine Tumor Associated with Tuberous Sclerosis Complex: A Case Report

Abstract Pancreatic neuroendocrine tumors (PNETs) are rare. They can be sporadic or associated with hereditary syndromes. The tuberous sclerosis complex (TSC) is associated with the occurrence of PNETs in about 1% of cases. Diagnosis of the tumor is made with biochemical markers and imaging techniques. Management in these cases remains controversial. We report a case of a 46-year-old male patient with a prior diagnosis of TSC and imaging findings of a pancreatic tumor. Clinical suspicion is essential in patients with predisposing conditions and requires evaluation by a multidisciplinary team. Keywords: Pancreatic neuroendocrine tumor; tuberous sclerosis complex, genetic disorder.