A Comprehensive Review on Transmucosal Patch for Oral Ulcer

Oral ulcers are frequently caused by trauma, systemic problems or idiosyncratic reasons, infections thus lead to more painful condition which impacts the mucosal lining of the mouth cavity. Major problems associated with traditional therapies comprises repeated dosage, inadequate retention rate as well as insufficient bioavailability. These consists of gel like formulation, mouthwashes and systemic therapies. Transmucosal films serves as a possibly efficient replacement for the oral delivery of medication for curing mouth ulcers. Defined release of medication, longer duration of contact, greater bioavailability and improved compliance among patient are some of the positives associated with these patches. The present article contains an in-depth discussion of transmucosal patches aimed for the treatment treating mouth ulcers, thus covers different methods of preparation of transmucosal patches, polymer types, Mucoadhesion mechanism and its theories, drug release mechanisms, and evaluation methods. The review paper additionally addresses possible potential futures regarding clinical use of this innovative treatment strategy along with latest advances in mucoadhesive techniques.