ASSOCIATING CARDIOVASCULAR DISEASES WITH BODY FAT MASS INDICES AND BARORECEPTOR SENSITIVITY IN POSTMENOPAUSAL WOMEN WITH HIGH BODY MASS INDEX

Body fat accumulation can vary baroreceptor sensitivity and that finally will have effect on body as altered blood pressure, glucose levels, and cardiovascular disorders, making it a significant public health concern among postmenopausal women with reduction in their average lifespan. High body mass index can impair baroreflex function and lower BRS, mostly via increasing sympathetic nervous system activity. Aims and Objectives: The aim of the study is to Associate cardiovascular diseases with body fat mass indices and Baroreceptor sensitivity in normal and high body mass index (BMI) postmenopausal women. Materials and Methods: This research was directed on 104 postmenopausal women of age group 45–60 years grouped them into two. Group 1 having normal BMI (18.50–24.99) and Group 2 having high BMI >25.00 based on Asian’s classification for BMI. Approval from the Institutional Ethical Committee was obtained before beginning the study. The continuous beat to beat blood pressure variability is measured using a noninvasive continuous hemodynamic monitor Finapres and Body fat composition was measured using an equipment named Bodystat that uses the technique of bioelectrical impedence analysis. Statistical analysis: Unpaired t-test was used to analyze all parameters of the study (control and study group). The result showed a lower level of parasympathetic and a higher sympathetic activity in the high BMI postmenopausal women when matched against the control group. Conclusion: Body fat mass indices and BRS are inversely proportional in high BMI postmenopausal women and they more likely to suffer from cardiometabolic disorders in early when compared to normal BMI postmenopausal women.