Necrobiosis lipoidica as a cutaneous marker of underlying metabolic and autoimmune disorders: A case report

Introduction: Necrobiosis lipoidica is a very rare and chronic disease characterized by yellow-brown, atrophic, telangiectatic changes that occur mostly on the lower extremities. It is characterized by the appearance of collagen necrobiosis and dermal inflammation. Case report: A 50-year-old patient with changes on both lower legs that date back to a year ago and for which she never sought medical help complains of the appearance of an ulcer two weeks ago on one of the changes after a minor trauma. Conclusion: Necrobiosis lipoidica is a rare granulomatous disease associated with diabetes and autoimmune diseases that patients have already diagnosed, but in our case the skin changes were the first that led us to additional research and diagnosis of diabetes and rheumatoid arthritis.

Institutions

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-03-30
DOI
https://doi.org/10.5281/zenodo.16993728
Primary Topic
Geochemistry and Geologic Mapping
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Necrobiosis lipoidica as a cutaneous marker of underlying metabolic and autoimmune disorders: A case report

Zenodo (CERN European Organization for Nuclear Research)
Geochemistry and Geologic Mapping
article

Necrobiosis lipoidica as a cutaneous marker of underlying metabolic and autoimmune disorders: A case report

article en

Abstract

Introduction: Necrobiosis lipoidica is a very rare and chronic disease characterized by yellow-brown, atrophic, telangiectatic changes that occur mostly on the lower extremities. It is characterized by the appearance of collagen necrobiosis and dermal inflammation. Case report: A 50-year-old patient with changes on both lower legs that date back to a year ago and for which she never sought medical help complains of the appearance of an ulcer two weeks ago on one of the changes after a minor trauma. Conclusion: Necrobiosis lipoidica is a rare granulomatous disease associated with diabetes and autoimmune diseases that patients have already diagnosed, but in our case the skin changes were the first that led us to additional research and diagnosis of diabetes and rheumatoid arthritis.

Zenodo (CERN European Organization for Nuclear Research)
Institute of public health of Republic of Macedonia (MK), Goce Delcev University (MK)
Good health and well-being
Openalex Percentile: Top 60%
Geochemistry and Geologic Mapping
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Necrobiosis lipoidica as a cutaneous marker of underlying metabolic and autoimmune disorders: A case report · Zenodo (CERN European Organization for Nuclear Research) (2025) | TGRS Research Map | TGRS