A Comprehensive Review on Chikungunya Virus Epidemiology, Pathogenesis, Clinical Manifestations, Treatment and Current Vaccine Development

The current outbreak in the Americas was caused by the re-emerging mosquito-borne alphavirus called the Chikungunya virus (CHIKV). The Americas' immunologically native population encourages the spread of diseases. The current outbreak in the Americas was caused by the re-emerging mosquito-borne alphavirus known as the Chikungunya virus. The Americas' immunologically native population encourages the spread of diseases.Maculopapular rash, polyarthralgia, and a sudden feverish sickness are the hallmarks of chikungunya fever. Shock or major bleeding are extremely uncommon with chikungunya fever; the illness has a more violent start and a shorter fever duration than dengue. The illness is now prevalent throughout the nation, with outbreaks causing significant losses in production and the economy. Chronicity, severe infections, elevated hospitalization risks, and related mortality are all part of the burden of chikungunya disease. The illness can have a substantial influence on national economies and the health system, among other areas of the economy. It is crucial to comprehend and quantify the entire effects of this reemerging illness.Chronicity, severe infections, elevated hospitalization risks, and related mortality are all part of the burden of chikungunya illness. The illness has the potential to have a substantial influence on both national economies and the health system in a number of ways. It is crucial to comprehend and quantify the whole consequences of this reemerging illness.