Therapeutic use of psilocybin in the management of chonic pain: a scoping review

Chronic pain is a multifactorial and debilitating condition that significantly impacts quality of life and functionality. Conventional therapeutic options often have limited efficacy or significant adverse effects. In this context, psychedelic compounds such as psilocybin and its active form, psilocin, have emerged as potential therapeutic agents for managing chronic pain due to their modulating effects on sensory perception, neuroplasticity, and emotional state.