Development and Assessment of Herbal Anti-Aging Cream Using Okra Mucilage and Rice Extracts

<p><span>Background:<span>  </span>Skin aging is a complex process that destroys human skin when exposed to ultraviolet (UV) irradiation on a continuous basis. Skin wrinkling eventually results from a lack of collagen caused by reactive oxygen species produced by UV light exposure. Numerous phenolics and flavonoids found in basil have antioxidant qualities. This study aimed to create and evaluate an anti-aging face cream using rice extract, okra mucilage acetone extract, and okra mucilage extract extracts. Method:<span>  </span>Various formulations of oil-in-waterin water (O/W) anti-aging creams, designated as F1 to F6, were prepared with different concentrations of okra mucilage extract, acetone extract of okra mucilage, rice extract, and linseed oil. Each formulation underwent a comprehensive evaluation for pH level, viscosity, Spreadability, sensory attributes, homogeneity, appearance, and stability. To ensure safety even more, irritancy tests were performed. The formulations F1, F2, and F6 demonstrated advantageous characteristics such as Spreadability, homogeneity, uniformity, aesthetic appeal, and pH balance. Furthermore, they exhibited ease of removal without evidence of phase separation. Irritancy studies confirmed that no one of the formulations caused redness, swelling, inflammation, or irritation, indicating their suitability for skin application.<span>  </span>Results: The main purpose behind this investigation was to develop a stable and functionally effective cream and to evaluate for good product performance of the prepared cream. The pH of the cream was found to be in the range of 6.3 to 6.9 which is good for skin pH. All the formulations of cream were shown pH nearer to skin required i.e.</span><span> <span lang="EN-IN">All the formulations of cream were shown pH nearer to skin required i.e pH of F1-6.31, F2-6.22, F3-6.43, F4-6.66, F5-6.57, and F6-6.70.</span></span> <span lang="EN-IN">The dye test confirms that all formulations were o/w type emulsion cream. But formulation (F1, F2 & F6) shows more stability in o/w type emulsion. </span><span lang="EN-GB">All formulations produce a uniform distribution of extracts in cream. The formulations applied to the skin was easily removed by washing with tap water. All formulation shows no redness, edema, inflammation or irritation during irritancy studies. These formulations are safe to use for the skin. Accelerated stability testing of prepared formulations was conducted for all formulations at 40°C 1°C for 20 days. The formulations were kept both at room and elevated temperature and observed 20th day for the various parameters. Conclusion: Both the okra and rice extract formulations showed potent antioxidant activities and tyrosinase inhibition. The findings from these studies indicate that the formulation comprising okra and rice extracts, specifically F1, F2, and F6, exhibit higher levels of stability and safety compared to the other formulations. Conversely, the remaining formulations demonstrated instability and exhibited changes in color upon prolonged storage. As we know that itis not possible to increase the extent of efficiency of medicinal and cosmetic property of single plant extract, but by combining the different natural components can be possible to increase the efficacy of extracts. The results demonstrated that the formulated antiaging creams are safe and usable for the skin and having good potential for cosmetic product development.</span></p>