Phytochemical Profiling and GC-MS Analysis of Bioactive Compounds in Guiera Senegalensis Leaves Extract

ABSTRACT Medicinal plants have been used extensively as sources of a wide variety of biologically active compounds for many centuries and as crude materials or pure compounds for treating various disease conditions. The plant leaves were extracted with hexane and methanol using the Soxhlet extraction process. The Phytochemical tests were carried out on the extracts using standard procedures to identify the constituents. The result obtained revealed the presence of Flavonoids, Tannins, Phenols, and Triterpenes in Methanol and n-Hexane extracts. Saponins, Alkaloids, and Cardiac glycosides were present in Methanol but absent in n-hexane extract. Anthraquinones were absent in both extracts. The leaves of the plant have been applied in treating snakebite, stomach ache, cough, and so on. Characterization of the extracts was done using GC-MS analysis. GC-MS analysis revealed the presence of 50 compounds from which 14, 4, 15, 13, and 13 were for hexane, chloroform, ethyl acetate, butanol, and aqueous fractions, respectively. The results of this study supported the use of G. senegalensis in traditional medicine by demonstrating that its leaves contain phytoconstituents. Keywords: Guiera senegalensis , Phytochemicals, GC-MS