Chanting 'Om': A Neurochemical Pathway to Calm - Exploring GABAergic and Serotonergic Mechanisms

<p><span>The ancient practice of chanting 'Om' has gained considerable attention in neuroscientific research for its potential therapeutic effects on stress reduction and emotional regulation. This review examines the neurochemical mechanisms underlying the calming effects of Om chanting, with particular focus on GABAergic and serotonergic pathways. Through systematic analysis of current literature, we explore how the vibrational frequencies and meditative aspects of Om chanting influence neurotransmitter systems, particularly gamma-aminobutyric acid (GABA) and serotonin networks. The evidence suggests that Om chanting activates parasympathetic nervous system responses, modulates stress hormone levels, and enhances inhibitory neurotransmission through multiple neurochemical pathways. These findings provide a scientific foundation for understanding how traditional contemplative practices can produce measurable neurobiological changes associated with relaxation and emotional well-being. Further research is needed to establish standardized protocols and identify individual variations in response to this ancient practice</span><span>.</span></p>