A Review on Healing at the Surface: Exploring the Power of Antimicrobial Cream Formulation

Creams have long been used as topical preparations due to their ease of application and removal from the skin. Pharmaceutical creams serve a wide range of purposes, from cosmetic uses such as cleansing, moisturizing, enhancing appearance, and beautifying, to therapeutic applications like protecting the skin against bacterial and fungal infections, and aiding in the healing of cuts, burns, and wounds [6]. Topical application offers several advantages over systemic therapy, including the ability to deliver high and sustained drug concentrations directly to the site of infection, reduced dosage requirements, improved patient compliance, fewer systemic side effects, and a potentially lower risk of developing antimicrobial resistance [8]. This review focuses on the use of topical drug delivery systems, specifically pharmaceutical creams, in wound healing. It provides a detailed discussion of the wound healing process, classification of creams based on their functions, their advantages and disadvantages, key characteristics, and the various types of creams available.[7].