<i>In</i> <i>Vitro</i> Efficacy of 222 nm UV Light on Antibiotic Resistant Bacteria Isolated from Patients and Standart Cultures Standard Bacterial Strains

Aims: We observed in vitro effects of a filtered 222 nm Far-UVC device (Initus-V) on antibiotic resistant bacteria taken from hospitalized patients and standart antibiotic resistant bacterial cultures by exposing them to filtered 222 nm Far-UVC for 5, 15, 30, 45 and 60 minutes. Method: Blood culture samples taken from septic patients hospitalized in Istinye University Hospital in 2022 were inoculated into Petri dishes and antibiotic resistance bacteria were grown. Experiment group bacteria were exposed to 222 nm Far-UVC system while control group was not exposed. Initus-V 222 light from emits 42.9 uW/cm2 energy at a distance of 50 cm from the source. Bacterial growth and Log reduction values at 24 and 48 hours were calculated for both groups. Conclusion: In all antibiotic resistant bacterial cultures obtained either from patients or standart commercial sources growth was inhibited to 0 at 30 minutes except Klebsiella pneumonia obtained from patients in which there was 8 log reduction at 30 minutes. Filtered Far-UVC can have place in future treatment of antibiotic resistant bacteria and spread of hospital acquired infections because preliminary animal trials show its safety within certain limits.