44‐2: Optogenetic Manipulation of Neurons Using Organic Light‐Emitting Diodes

We developed tandem‐structured blue and yellow OLEDs optimized for optogenetics, achieving peak optical power densities of ~3.1 mW/mm ² and ~3.8 mW/mm ² , respectively. The emission spectra were matched to the activation spectra of opsins like ChR2 and Arch, enabling effective neuronal activation and inhibition. With a custom‐made 64‐channel MEA, we demonstrated precise temporal correlations between OLED stimulation and neuronal responses. These results establish OLEDs as promising light sources for optogenetic applications.

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Publication Details

Journal
SID Symposium Digest of Technical Papers
Published
2025-06-01
DOI
https://doi.org/10.1002/sdtp.18227
Primary Topic
Geochemistry and Geologic Mapping
Type
article
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article

44‐2: Optogenetic Manipulation of Neurons Using Organic Light‐Emitting Diodes

SID Symposium Digest of Technical Papers
Geochemistry and Geologic Mapping
article

44‐2: Optogenetic Manipulation of Neurons Using Organic Light‐Emitting Diodes

article en

Abstract

We developed tandem‐structured blue and yellow OLEDs optimized for optogenetics, achieving peak optical power densities of ~3.1 mW/mm ² and ~3.8 mW/mm ² , respectively. The emission spectra were matched to the activation spectra of opsins like ChR2 and Arch, enabling effective neuronal activation and inhibition. With a custom‐made 64‐channel MEA, we demonstrated precise temporal correlations between OLED stimulation and neuronal responses. These results establish OLEDs as promising light sources for optogenetic applications.

SID Symposium Digest of Technical PapersVol. 56(1)
Seoul National University (KR), Electronics and Telecommunications Research Institute (KR)
Openalex Percentile: Top 70%
Geochemistry and Geologic Mapping
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