The impact of maternal mental health disorders on fetal neurodevelopment-considering sociodemographic factors: A systematic literature review

Pregnancy is a critical period for fetal development, which is influenced by the mother’s psychological condition. This systematic literature review explores the latest findings related to the impact of maternal mental health during pregnancy influenced by sociodemographic factors on fetal neurodevelopmental disorders. This review synthesizes findings from articles published between 2015 and 2025 in the Scopus, PubMed, and ScienceDirect databases, following the PRISMA guidelines. The search results yielded 1,140 articles; after applying the filtering process, the final result was 20 articles that met the inclusion and exclusion criteria. The mental health of pregnant women, especially when experiencing stress, anxiety, or depression, has a tangible impact on the formation of fetal brain structure and function. Social factors such as low economic status, low maternal Education and social support, limited access to health services, and global crises such as the COVID-19 pandemic can worsen maternal mental health and affect fetal brain development. The importance of a comprehensive approach that includes mental health services during pregnancy and social support can be used as an effort to prevent neurological developmental disorders in the fetus.

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Publication Details

Journal
E3S Web of Conferences
Published
2025-01-01
DOI
https://doi.org/10.1051/e3sconf/202564003005
Primary Topic
Theoretical and Computational Physics
Type
article
Field-Weighted Citation Impact
0.00
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article

The impact of maternal mental health disorders on fetal neurodevelopment-considering sociodemographic factors: A systematic literature review

E3S Web of Conferences
Theoretical and Computational Physics
article

The impact of maternal mental health disorders on fetal neurodevelopment-considering sociodemographic factors: A systematic literature review

article en

Abstract

Pregnancy is a critical period for fetal development, which is influenced by the mother’s psychological condition. This systematic literature review explores the latest findings related to the impact of maternal mental health during pregnancy influenced by sociodemographic factors on fetal neurodevelopmental disorders. This review synthesizes findings from articles published between 2015 and 2025 in the Scopus, PubMed, and ScienceDirect databases, following the PRISMA guidelines. The search results yielded 1,140 articles; after applying the filtering process, the final result was 20 articles that met the inclusion and exclusion criteria. The mental health of pregnant women, especially when experiencing stress, anxiety, or depression, has a tangible impact on the formation of fetal brain structure and function. Social factors such as low economic status, low maternal Education and social support, limited access to health services, and global crises such as the COVID-19 pandemic can worsen maternal mental health and affect fetal brain development. The importance of a comprehensive approach that includes mental health services during pregnancy and social support can be used as an effort to prevent neurological developmental disorders in the fetus.

E3S Web of ConferencesVol. 640
Muhammadiyah University of Yogyakarta (ID), Universitas Negeri Surabaya (ID), Myanmar Oxford Clinical Research Unit (MM), National Cheng Kung University Hospital (TW), National Cheng Kung University (TW)
Reduced inequalities
Openalex Percentile: Top 45%
Theoretical and Computational Physics
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The impact of maternal mental health disorders on fetal neurodevelopment-considering sociodemographic factors: A systematic literature review · E3S Web of Conferences (2025) | TGRS Research Map | TGRS