Acute Bowel Obstruction: A Rare Circumstance of Prostate Cancer Discover

Introduction: Prostate cancer is the leading cancer in incidence and mortality in Ivory Coast.The diagnosis is most often made at locally invasive or metastatic stages.However, extension to the rectum with acute digestive symptoms is rare, and can mimic primary rectal cancer. Case presentation:We reported a case of a 69-year-old patient who presented with acute bowel obstruction due to a tumor filling the rectal lumen.The initial diagnosis of rectal cancer was revoked by histological analysis of the biopsy of this tumor which concluded that it was acinar adenocarcinoma of the prostate Gleason 9 (4+5) confirmed with immunohistochemical staining for prostate specific antigen.We performed colostomy followed by Androgen Deprivation Therapy (ADT) combined to chemotherapy.The evolution 11 months after surgery was marked by the occurrence of resistance to castration.The indication for second-line treatment with abiraterone acetate was not observe by the patient and the patient's death occurred in the 15th month following surgery. Conclusion:Acute bowel obstruction due to rectal involvement by prostate cancer is rare and mimics rectal cancer.Histopathology and immunohistochemistry are essential for accurate diagnosis.

Publication Details

Journal
Journal of Urology and Renal Diseases
Published
2025-07-30
DOI
https://doi.org/10.29011/2575-7903.001429
Primary Topic
Geochemistry and Geologic Mapping
Type
article
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article

Acute Bowel Obstruction: A Rare Circumstance of Prostate Cancer Discover

Journal of Urology and Renal Diseases
Geochemistry and Geologic Mapping
article

Acute Bowel Obstruction: A Rare Circumstance of Prostate Cancer Discover

article en

Abstract

Introduction: Prostate cancer is the leading cancer in incidence and mortality in Ivory Coast.The diagnosis is most often made at locally invasive or metastatic stages.However, extension to the rectum with acute digestive symptoms is rare, and can mimic primary rectal cancer. Case presentation:We reported a case of a 69-year-old patient who presented with acute bowel obstruction due to a tumor filling the rectal lumen.The initial diagnosis of rectal cancer was revoked by histological analysis of the biopsy of this tumor which concluded that it was acinar adenocarcinoma of the prostate Gleason 9 (4+5) confirmed with immunohistochemical staining for prostate specific antigen.We performed colostomy followed by Androgen Deprivation Therapy (ADT) combined to chemotherapy.The evolution 11 months after surgery was marked by the occurrence of resistance to castration.The indication for second-line treatment with abiraterone acetate was not observe by the patient and the patient's death occurred in the 15th month following surgery. Conclusion:Acute bowel obstruction due to rectal involvement by prostate cancer is rare and mimics rectal cancer.Histopathology and immunohistochemistry are essential for accurate diagnosis.

Journal of Urology and Renal DiseasesVol. 10(8)
Good health and well-being
Openalex Percentile: Top 71%
Geochemistry and Geologic Mapping
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Acute Bowel Obstruction: A Rare Circumstance of Prostate Cancer Discover · Journal of Urology and Renal Diseases (2025) | TGRS Research Map | TGRS