Complications And Adverse Drug Reaction Occurrence in Human Immunodeficiency Virus and Extra-Pulmonary Tuberculosis Co-Infected Individuals: An Educational Case Report

<p><span>Human immunodeficiency virus (HIV) positive individuals are highly susceptible to extrapulmonary tuberculosis (EPTB) and other opportunistic infections due to immune suppression. The co-administration of antiretroviral therapy (ART) and anti-tuberculosis therapy (ATT) often causes overlapping adverse effects, creating significant treatment challenges. This case report illustrates the clinical complexity in managing a patient with HIV and EPTB who developed oral candida infection, acute gastritis, and anemia shortly after starting ATT. Supportive care, including antifungal therapy, symptomatic treatment, and iron supplementation, was crucial in addressing these complications while continuing ART and ATT. The case highlights the importance of close monitoring and prompt intervention to prevent treatment interruptions and achieve favorable clinical outcomes in HIV and tuberculosis (TB) co-infected patients</span><span lang="EN-IN">.</span><span lang="EN-IN"> </span></p>

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2025-08-18
DOI
https://doi.org/10.5281/zenodo.16892333
Primary Topic
Theoretical and Computational Physics
Type
article
Field-Weighted Citation Impact
0.00
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article

Complications And Adverse Drug Reaction Occurrence in Human Immunodeficiency Virus and Extra-Pulmonary Tuberculosis Co-Infected Individuals: An Educational Case Report

Zenodo (CERN European Organization for Nuclear Research)
Theoretical and Computational Physics
article

Complications And Adverse Drug Reaction Occurrence in Human Immunodeficiency Virus and Extra-Pulmonary Tuberculosis Co-Infected Individuals: An Educational Case Report

article en

Abstract

<p><span>Human immunodeficiency virus (HIV) positive individuals are highly susceptible to extrapulmonary tuberculosis (EPTB) and other opportunistic infections due to immune suppression. The co-administration of antiretroviral therapy (ART) and anti-tuberculosis therapy (ATT) often causes overlapping adverse effects, creating significant treatment challenges. This case report illustrates the clinical complexity in managing a patient with HIV and EPTB who developed oral candida infection, acute gastritis, and anemia shortly after starting ATT. Supportive care, including antifungal therapy, symptomatic treatment, and iron supplementation, was crucial in addressing these complications while continuing ART and ATT. The case highlights the importance of close monitoring and prompt intervention to prevent treatment interruptions and achieve favorable clinical outcomes in HIV and tuberculosis (TB) co-infected patients</span><span lang="EN-IN">.</span><span lang="EN-IN"> </span></p>

Zenodo (CERN European Organization for Nuclear Research)
Good health and well-being
Openalex Percentile: Top 50%
Theoretical and Computational Physics
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