Leveraging the RETFound foundation model for optic disc segmentation in retinal images

RETFound is a well-known foundation model (FM) developed for fundus camera and optical coherence tomography images. It has shown promising performance across multiple datasets in diagnosing diseases, both eye-specific and systemic, from retinal images. However, to our best knowledge, it has not been used for other tasks. We present the first adaptation of RETFound for optic disc segmentation, a ubiquitous and foundational task in retinal image analysis. The resulting segmentation system outperforms state-of-the-art, segmentation-specific baseline networks after training a head with only a very modest number of task-specific examples. We report and discuss results with four public datasets, IDRID, Drishti-GS, RIM-ONE-r3, and REFUGE, and a private dataset, GoDARTS, achieving about 96% Dice consistently across all datasets. Overall, our method obtains excellent performance in internal verification, domain generalization and domain adaptation, and exceeds most of the state-of-the-art baseline results. We discuss the results in the framework of the debate about FMs as alternatives to task-specific architectures. The code is available at: [link to be added after the paper is accepted]

Publication Details

Journal
arXiv (Cornell University)
Published
2025-08-15
Primary Topic
Theoretical and Computational Physics
Type
article
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article

Leveraging the RETFound foundation model for optic disc segmentation in retinal images

arXiv (Cornell University)
Theoretical and Computational Physics
article

Leveraging the RETFound foundation model for optic disc segmentation in retinal images

article en

Abstract

RETFound is a well-known foundation model (FM) developed for fundus camera and optical coherence tomography images. It has shown promising performance across multiple datasets in diagnosing diseases, both eye-specific and systemic, from retinal images. However, to our best knowledge, it has not been used for other tasks. We present the first adaptation of RETFound for optic disc segmentation, a ubiquitous and foundational task in retinal image analysis. The resulting segmentation system outperforms state-of-the-art, segmentation-specific baseline networks after training a head with only a very modest number of task-specific examples. We report and discuss results with four public datasets, IDRID, Drishti-GS, RIM-ONE-r3, and REFUGE, and a private dataset, GoDARTS, achieving about 96% Dice consistently across all datasets. Overall, our method obtains excellent performance in internal verification, domain generalization and domain adaptation, and exceeds most of the state-of-the-art baseline results. We discuss the results in the framework of the debate about FMs as alternatives to task-specific architectures. The code is available at: [link to be added after the paper is accepted]

arXiv (Cornell University)
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Theoretical and Computational Physics
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