Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines

The synthesis and full characterization of new hydroxyl benzo[a]phenoxazinium chlorides with N-(di)propyl and/or N-isopropyl groups in the 5 and 9 positions are described. Photophysical studies carried out in ethanol and water revealed strong absorbances and significant fluorescence emissions at up to 676 nm. The antifungal activity was assessed against Saccharomyces cerevisiae and the results provide possible directions for further studies.

Publication Details

Journal
Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
Published
2024-10-15
Primary Topic
Theoretical and Computational Physics
Type
article
Field-Weighted Citation Impact
0.00

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article

Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines

Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
Theoretical and Computational Physics
article

Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines

article en

Abstract

The synthesis and full characterization of new hydroxyl benzo[a]phenoxazinium chlorides with N-(di)propyl and/or N-isopropyl groups in the 5 and 9 positions are described. Photophysical studies carried out in ethanol and water revealed strong absorbances and significant fluorescence emissions at up to 676 nm. The antifungal activity was assessed against Saccharomyces cerevisiae and the results provide possible directions for further studies.

Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
China Building Materials Academy, Fundação para a Ciência e a Tecnologia
Clean water and sanitation
Openalex Percentile: Top 62%
Theoretical and Computational Physics
Open Access PDFOpenAlex
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Synthesis, photophysics, and potential antifungal activity of Benzo[a]phenoxazines · Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (2024) | TGRS Research Map | TGRS