The contribution of type 2 diabetes to Parkinson's disease aetiology

Type 2 diabetes (T2D) and Parkinson's disease (PD) are chronic disorders that have a significant health impact on a global scale. Epidemiological, preclinical, and clinical research underpins the assumption that insulin resistance and chronic inflammation contribute to the overlapping aetiologies of T2D and PD. This narrative review summarises the recent evidence on the contribution of T2D to the initiation and progression of PD brain pathology. It also briefly discusses the rationale and potential of alternative pharmacological interventions for PD treatment.

Publication Details

Journal
Repository of the University of Ljubljana (University of Ljubljana)
Published
2024-11-18
Primary Topic
Seismic Imaging and Inversion Techniques
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article
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article

The contribution of type 2 diabetes to Parkinson's disease aetiology

Repository of the University of Ljubljana (University of Ljubljana)
Seismic Imaging and Inversion Techniques
article

The contribution of type 2 diabetes to Parkinson's disease aetiology

article en

Abstract

Type 2 diabetes (T2D) and Parkinson's disease (PD) are chronic disorders that have a significant health impact on a global scale. Epidemiological, preclinical, and clinical research underpins the assumption that insulin resistance and chronic inflammation contribute to the overlapping aetiologies of T2D and PD. This narrative review summarises the recent evidence on the contribution of T2D to the initiation and progression of PD brain pathology. It also briefly discusses the rationale and potential of alternative pharmacological interventions for PD treatment.

Repository of the University of Ljubljana (University of Ljubljana)
Good health and well-being
Openalex Percentile: Top 45%
Seismic Imaging and Inversion Techniques
Open Access PDFOpenAlex
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The contribution of type 2 diabetes to Parkinson's disease aetiology · Repository of the University of Ljubljana (University of Ljubljana) (2024) | TGRS Research Map | TGRS