Macrostructural Brain Abnormalities in Spinal Muscular Atrophy A Case-Control Study

Background and ObjectivesMost individuals with spinal muscular atrophy (SMA) on disease-modifying therapies continue to have chronic motor impairment.Insights into brain involvement in SMA may open new pathways for adjunctive therapies to optimize outcomes.We aimed to characterize macrostructural brain abnormalities detected by MRI in individuals with SMA compared with peer controls.

Publication Details

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eScholarship@McGill (McGill)
Published
2024-09-20
Primary Topic
Seismic Waves and Analysis
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article
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article

Macrostructural Brain Abnormalities in Spinal Muscular Atrophy A Case-Control Study

eScholarship@McGill (McGill)
Seismic Waves and Analysis
article

Macrostructural Brain Abnormalities in Spinal Muscular Atrophy A Case-Control Study

article en

Abstract

Background and ObjectivesMost individuals with spinal muscular atrophy (SMA) on disease-modifying therapies continue to have chronic motor impairment.Insights into brain involvement in SMA may open new pathways for adjunctive therapies to optimize outcomes.We aimed to characterize macrostructural brain abnormalities detected by MRI in individuals with SMA compared with peer controls.

eScholarship@McGill (McGill)
Openalex Percentile: Top 47%
Seismic Waves and Analysis
Open Access PDFOpenAlex
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Macrostructural Brain Abnormalities in Spinal Muscular Atrophy A Case-Control Study · eScholarship@McGill (McGill) (2024) | TGRS Research Map | TGRS