АНЕСТЕЗІОЛОГІЧНА СМЕРТЬ. ПРОБЛЕМА ТА СТАТИСТИКА (ЛІТЕРАТУРНИЙ ОГЛЯД)

Introduction. Prevention of anesthesia mortality is a medical and social problem that has been gradually implemented over the last century thanks to various social and medical measures. Evidence of obtaining information. Articles of choice were included in the study if they were published in Ukrainian, English, French and Portuguese; reported on anesthesia-related deaths; reported on the prevalence of perioperative mortality; used an observational study design (cohort or cross-sectional). Materials and methods. Obtaining literary scientific information was carried out using the information search systems Scopus, Google Scholar, CrossRef and PubMed, which was also supplemented by a manual search of the used articles using the key terms: anesthesia; anesthesia mortality; mortality during anesthesia; perioperative mortality. Evidence synthesis. The concept of «complications of anesthesia» includes mortality and morbidity associated with anesthesia. The American Society of Anesthesiologists conducted a meta-analysis to identify mortality from anesthesia and during anesthesia. Anesthesia-related mortality tends to decrease more significantly in developed countries (ten times faster) than in low-income countries. The probability of anesthesia-related death in elective surgery is 1:200,000- 1:300,000, and in emergency surgery it is three times higher. The risk of death within 30 days of surgery under general anesthesia increases by 1% with each additional year. Patients with ASA class III or IV have a 7.3-fold higher rate of anesthesia-related mortality than patients with class I or II. Conclusions. Anesthesia-related mortality is largely due to the intervention of a new, often unexpected factor in the treatment process. The problem of patient safety during surgical treatment and anesthesia remains relevant today. The implementation of modern versions of the incident monitoring and reporting system of the anesthesia service of Ukraine will allow optimizing perioperative patient safety in the future.