Synthesis of a Dipeptide and Investigation of Its Antimicrobial Activity

Dipeptides can be synthesized for numerous purposes, one of the possible functions is as an antimicrobial agent. A dipeptide will be synthesized from two different amino acids. The N-terminus of one amino acid will be protected using a BOC protecting group while the C-terminus of the other amino acid will be protected by undergoing a Fischer Esterification reaction. The protected amino acids will then undergo liquid phase coupling using EDC to synthesize the final selected dipeptide. The lab synthesized dipeptide will then be tested and analyzed to determine if it exhibits any antimicrobial activity.