Synthesis, Structural Characterization, and Biomedical Potential of Non-Natural Palladium-Amino Acid Complexes

The focus of this project is to synthesize and characterize unique organometallic Palladium complexes with various Non-Natural amino acid (AA) ligands. We will describe our synthetic pathway and present and discuss Fourier-transform infrared, 1H and 13C nuclear magnetic resonance, UV-visible, mass spectrometry, and elemental analysis data. These compounds are expected to show both catalytic and biological activity; the final aim of the study is to evaluate their potential utilization in future medical applications with a primary focus on cancer treatment and antimicrobial activity, including evaluation via the Kirby-Bauer Disk Diffusion Susceptibility Test.