Plantas medicinais e fitoterápicos com potencial antifúngico na região Norte-Amazônica

Objective: The purpose of this systematic review is to evaluate the efficacy and safety of the use of medicinal plants and phytotherapeutics that are used in the North Amazon region in the treatment of vaginitis and vaginosis. Method: A systematic search was performed in the PubMed, Lilacs, Google Scholar and Scielo databases, using the terms "medicinal plants", "phytotherapeutics", "vaginitis", "antifungal", "fungicide" and others. Studies that evaluated the efficacy and safety of medicinal plants and phytotherapeutics in the treatment of vaginitis and vaginosis in humans were selected. Results: Of the 9 medicinal plants used in this systematic review, 7 are recommended by RENISUS, the aroeira (Schinus terebinthifolius) and espinheira-santa (maytenus ilicifolia) are already considered safe to use. Others such as losna (Artemisa absinthium), pitangueira, copaíba, goiabeira and barbatimão are also recommended and have been viewed with great interest. During the preparation of the study, sucupira was discarded due to obstacles in finding studies regarding its antifungal potential and related to gynecology on the platforms and languages used. Final considerations: The present review work on ‘Medicinal plants and phytotherapeutics with antifungal potential in the northern Amazon region’ concluded that the phytotherapy of these, in apractical way, requires further studies that enable the preparation of manuals and consequently the reduction of costs in treatments against pathogenic agents of Fungi origin.