Pancreatic Ganglioneuroma in the Elderly: A Rare Case in a 65-Year-Old Woman

Ganglioneuromas are rare benign tumors with favorable prognosis. Pancreatic ganglioneuromas are particularly uncommon, with only a few cases reported in the literature. Preoperative diagnosis can be challenging due to nonspecific radiological findings, difficult Fine needle aspiration (FNA) access, or inadequate sampling caused by the fibrous nature of the lesion. Surgical resection, followed by histopathological examination, remains the standard treatment approach. Herein, we report the case of a 65-year-old woman who presented with abdominal pain. Computed tomography (CT) suggested a diagnosis of lymphangioma or mucinous cystadenoma, but the final histopathological diagnosis confirmed the lesion to be ganglioneuroma. Hence, histopathology plays a significant role in accurate diagnosis of these lesions. Notably, to the best of our knowledge, this is the second reported case of pancreatic ganglioneuroma in the elderly population.