Numerical Investigation of Beta-Amyloid Aggregation Process In Alzheimer’s Disease

point indicates a condition where the monomer concentration is heading towards a value greater than zero.This condition occurs because the monomer continues to increase due to the aggregation process, but also decreases due to the degradation processes.From Eqs. (9), we can derived the component of interior equilibrium for 2 * , that isSubstitute Eq. ( 15) into Eqs.( 10)-( 14) we can obtain the component of interior equilibrium for 3 * , 4 * , 5 * , 6 * , * as followsThe value 1 * of can be determined by substituting Eqs. ( 15)-( 20) into Eq.( 8) and solve it for 1 * .Moreover, from those equations, it can be concluded that the component of interior equilibrium for 2 * , 3 * , , * have formula:

Publication Details

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Universitas Sanata Dharma Repository (Universitas Sanata Dharma)
Published
2025-01-01
Primary Topic
Cultural Competency in Health Care
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article

Numerical Investigation of Beta-Amyloid Aggregation Process In Alzheimer’s Disease

Universitas Sanata Dharma Repository (Universitas Sanata Dharma)
Cultural Competency in Health Care
article

Numerical Investigation of Beta-Amyloid Aggregation Process In Alzheimer’s Disease

article en

Abstract

point indicates a condition where the monomer concentration is heading towards a value greater than zero.This condition occurs because the monomer continues to increase due to the aggregation process, but also decreases due to the degradation processes.From Eqs. (9), we can derived the component of interior equilibrium for 2 * , that isSubstitute Eq. ( 15) into Eqs.( 10)-( 14) we can obtain the component of interior equilibrium for 3 * , 4 * , 5 * , 6 * , * as followsThe value 1 * of can be determined by substituting Eqs. ( 15)-( 20) into Eq.( 8) and solve it for 1 * .Moreover, from those equations, it can be concluded that the component of interior equilibrium for 2 * , 3 * , , * have formula:

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Numerical Investigation of Beta-Amyloid Aggregation Process In Alzheimer’s Disease · Universitas Sanata Dharma Repository (Universitas Sanata Dharma) (2025) | TGRS Research Map | TGRS