In-Hospital Risk Factors and Short-Term Outcomes for Subarachnoid Hemorrhage

Yao Liu, Cunsheng Wei Department of Neurology, The Affiliated Jiangning Hospital with Nanjing Medical University, Nanjing, Jiangsu, 211100, People’s Republic of ChinaCorrespondence: Cunsheng Wei, Department of Neurology, Affiliated Jiangning Hospital with Nanjing Medical University, 169 hushan Road, Nanjing, Jiangsu, 211100, People’s Republic of China, Tel +86 18262637236, Email [email protected]: To explore the relevant factors affecting the prognosis of subarachnoid hemorrhage.Methods: 284 patients with subarachnoid hemorrhage who were hospitalized in our hospital from January 1, 2022 to June 30, 2024 were selected and divided into a good prognosis group and a poor prognosis group according to the modified Rankin Scale (mRS) score. The general clinical data of the patients were also collected, and the independent risk factors affecting the poor prognosis of the patients were screened by univariate logistic regression analysis.Results: Patients with a favorable prognosis had a lower incidence rate of rebleeding (4.72% vs 17.65%; P =0.001), electrolyte disturbances (21.46% vs 41.18%; P < 0.001), lower respiratory tract infection (5.58% vs 35.29%; P < 0.001), urinary tract infection (1.72% vs 15.69%; P < 0.001) and gastrointestinal infection (2.15% vs 11.76%; P < 0.001) than patients with an unfavorable prognosis. Therefore, coinfection is an independent risk factor for prognosis. After adjusting for covariates, logistic regression analysis identified the prognosis of subarachnoid hemorrhage was related to coinfections (adjusted odds ratio =2.057; 95% CI: 1.516~2.791; P< 0.001).Conclusion: Coinfection is a very important independent risk factor affecting prognosis, and clinical care should focus on how to reduce coinfection during hospitalization in patients with subarachnoid hemorrhage and treat it aggressively to reduce mortality and disability and improve patient prognosis.Keywords: subarachnoid hemorrhage, prognosis, infections, risk factors, treatment