The frequency of paroxysmal tonic spasm in multiple sclerosis

BACKGROUND: Multiple sclerosis (MS) is one of the most important neurological diseases with autoimmune pathogenesis characterized by demyelination of the central nervous system (CNS) with various spectrum of neurological manifestations. The most common form which is the relapsing-remitting type can be presented with visual, sensory, motor, cerebellar, and sphincteric disturbances lasting for days or even months.