ANIMAL AND HUMAN HEALTH AND ANTIMICROBIAL RESISTANCE

Antimicrobial resistance (AMR) represents a formidable global health crisis, compelling the adoption of the One Health approach which integrates human, animal, and environmental health sectors. This publication examines the challenges and strategies in combating AMR, emphasizing the application of One Health principles, especially in resource-constrained settings. The paper outlines significant lessons learned from successful AMR interventions worldwide. Materials and methods: The methodology involves a literature review and analysis of scientific articles available in global databases dedicated to the issue of AMR, as well as materials related to the implementation of various strategies to combat AMR at the national and governmental levels. Results: Challenges identified relate to gaps in surveillance, education, international cooperation, and resource allocation in low-resource settings. The analysis further delves into future research implications, advocating for a deeper understanding of resistance mechanisms, the impact of interventions, the development of rapid diagnostics, vaccine research, and the exploration of alternative therapies. Examples from the European Union, Bangladesh, Canada, China, India, and the USA have been examined. Conclusions: The paper concludes by calling for intensified collaborative efforts to mitigate AMR and tailored strategies that recognize the diverse contexts of countries grappling with resource limitations. Suggesting that addressing AMR requires concerted global efforts, the publication outlines actionable strategies within the One Health framework to maintain the effectiveness of antimicrobials. The future direction emphasizes the significance of comprehensive surveillance, the impact evaluation of interventions, policy development, and community engagement in ensuring sustainable solutions to AMR.