UH-55 An Investigation of the Systemic Effects of Polycystic Syndrome (PCOS)

An Investigation of the Systemic Effects of Polycystic Syndrome (PCOS) Abstract Polycystic Syndrome (PCOS) is a common, yet complex, endocrine disorder that goes undiagnosed in 70% of reproductive-aged women. The National Institute of Health labels diagnostic criteria as: “The presence of clinical and/or biochemical hyperan-drogenism and oligomenorrhea/amenorrhea with anovulation” (Witchel et al., 2019). In simpler terms, this means that women with PCOS present elevated male hormone levels or problems with ovulation. Although this disorder cannot be pinpointed to one cause, factors such as insulin resistance, low grade inflammation, excess androgen, and genetics could potentially play a role. PCOS symptoms include irregular menstrual cycles, ovarian cysts, hormonal imbalances, and other elements that distinguish it from similar reproductive disorders. Aside from these notable reproductive symptoms, PCOS can present in other ways as well, including various metabolic issues (i.e insulin resistance, obesity, dyslipidemia). Our research aimed to investigate some of the more underscored systemic effects of the disorder. We conducted an extensive literature review to assess impacts of PCOS on the nervous, cardiovascular, lymphatic, metabolic, musculoskeletal, and integumentary systems. Further, we examined less studied potential long-term PSOC complications such as osteoporosis and diabetes. Since PCOS is an intricate, complicated condition, early diagnosis can bring significant changes in long term effects. Taking precautionary measures allows women to enjoy benefits such as improved reproductive health and increased quality of life. By highlighting PCOS and its widespread effects, we hope to motivate the high percentage of undiagnosed women to seek the care they deserve.