Synthesis, Characterization and Antibacterial Activity of Silver Nanoparticles Prepared from Benzoin Gum (Loban) Extract

Background: The rise of multi-drug resistance poses a significant challenge for treating infectious diseases. Nanotechnology-particularly the use of silver nanoparticles (AgNPs)-offers promising solutions. Objective: To synthesize AgNPs using benzoin (reducing and stabilizing agent) as an eco-friendly (green) approach followed by the evaluation of their antibacterial activity against multi-drug-resistant pathogens. Methodology: AgNPs were synthesized by reacting silver nitrate with benzoin extract. Formation of AgNPs was confirmed by UV–visible spectroscopy and Fourier-transform infrared (FTIR) spectroscopy. Antibacterial efficacy was tested against Gram-positive and Gram-negative bacterial strains. Result: The benzoin-mediated AgNPs exhibited significant antibacterial activity against all tested strains, with the greatest inhibition against Streptococcus faecalis. Conclusion: Benzoin-mediated green synthesis of AgNPs provides an eco-friendly method to produce potent antimicrobial agents, especially effective against drug-resistant pathogens.