Measurement of CP violation in D0->KsKs decays with a novel calibration method

This thesis describes a measurement of CP-asymmetry in D0->KsKs decays at LHCb, searching for a confirmation of CP violation in the charm sector. The analysis is based on new data collected by LHCb in 2024, after a substantial upgrade of the detector and trigger apparatus. The main part of the work is the development and validation of a new analysis technique allowing to exploit the larger samples collected by the upgraded LHCb detector by a novel calibration technique and reference sample, and its application to LHCb data to produce the current best measurement of this quantity.