Guided bone regeneration using xenograft and magnesium membrane for large bone and soft tissue defects in the anterior maxilla: a case report

Introduction: The extraction of severely compromised teeth often results in significant bone loss and soft tissue defects, posing challenges for subsequent prosthetic restorations. The application of a membrane to exclude non-osteogenic tissues from interfering with bone regeneration is a key principle of guided bone regeneration (GBR). Objective: This case report aims to present the clinical outcome of GBR using a xenograft and a magnesium membrane in a patient with a large bone and soft tissue defect following the extraction of upper central and lateral incisors. Materials and methods: A 38-year-old patient presented with severe form of periodontitis involving upper right central and lateral incisors, stage III, grade B. Post-extraction, GBR was performed using a xenograft and magnesium membrane. The defect site was thoroughly debrided, xenograft was placed and covered with the membrane to stabilize the graft and promote optimal bone regeneration. The site was sutured and a temporary PMMA bridge was placed. Results: At 5 months post op, clinical and radiographic evaluations revealed successful bone regeneration and soft tissue healing. These findings suggest that the combined use of a xenograft and slowly resorbable barrier membrane is effective for managing large bone and soft tissue defects in the anterior maxilla. Conclusion: The use of the magnesium membrane resulted in a satisfactory functional and aesthetic outcome. This approach offers a reliable solution for managing complex defects, facilitating successful prosthetic restorations in the anterior maxillary region. Keywords: xenograft, magnesium membrane, guided bone regeneration.