Posttravmatik epilepsi: klinik seyir ve müdahale stratejileri

Posttraumatic epilepsy (PTE) is a type of epilepsy characterized by recurrent and spontaneous seizures following traumatic brain injury (TBI). Many mechanisms such as disruption of the blood-brain barrier, glial cell activation, synaptic reorganization, excitatory-inhibitory imbalance and genetic predispositions have been shown to be effective in the epilepsy process. Clinical symptoms are directly related to the type and severity of trauma. Imaging methods such as EEG and MRI are critical in the diagnostic process. Seizures that start in the early period may be the precursor of permanent seizures in the later periods. Treatment focuses on prevention of seizures in the early period and long-term antiepileptic treatment in the late period. Neuromodulation and surgical techniques should be considered in drug-resistant cases. In addition, psychological support and lifestyle modifications play a complementary role in PTE treatment. Considering this information, PTE is not only a neurological treatment but also a health problem that requires a multidisciplinary approach.