Knowledge Mapping and Global Research Trends of Ginseng Polysaccharides: a Bibliometric Analysis with Visualizations from 1985 to 2023

Pingli Mo,1 Bowen Gao,2 Rui Wang,1 Shiying Huang,1 Qiugu Chen,1 Muxia Li,1 Jiazhen Wu,1,3 Shangbin Zhang,1 Jianping Chen1 1Shenzhen Key Laboratory of Hospital Chinese Medicine Preparation, Shenzhen Traditional Chinese Medicine Hospital, the Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, People’s Republic of China; 2Department of Traditional Chinese Medicine, the Seventh Affiliated Hospital of Sun Yat-Sen University, Shenzhen, People’s Republic of China; 3Shenzhen Bao’an Authentic TCM Therapy Hospital, Shenzhen, People’s Republic of ChinaCorrespondence: Shangbin Zhang; Jianping Chen, Shenzhen Traditional Chinese Medicine Hospital, No. 1 Fuhua Road, Futian District, Shenzhen, People’s Republic of China, Email [email protected]; [email protected]: Panax ginseng C. A. Meyer (Ginseng) has a lengthy historical background of utilization and is frequently utilized for the treatment and prevention of various diseases. In recent times, researchers have shown an increasing inclination towards investigating the extraction, purification, structural analysis, and pharmacological properties of polysaccharides present in ginseng. However, there was still a lack of comprehensive and integrated analysis of ginseng polysaccharides.Methods: This study employed the Web of Science Core Collection (WoSCC) as the data source and utilized software tools including Bibliometrix R Package, VOSviewer, and CiteSpace for the purpose of conducting data visualization and analysis of ginseng polysaccharides publications.Results: China emerged as the foremost and most impactful nation in the realm of ginseng polysaccharide research, fostering robust collaborative ties with Republic of Korea and the USA. Yifa Zhou was the most influential author and the International Journal of Biological Macromolecules exerted as the significant influence in this field. The reference DUBOIS M, 1956, ANAL CHEM, V28, P350 received the highest citations. Through a comprehensive examination results of keywords clustering, keywords with the strong burst, and trend topic, the research hot directions of ginseng polysaccharides were focused on structural analysis and pharmacological activities. Specifically, gut microbiota and oxidative stress were active research hotspots of investigating the pharmacological activities of ginseng polysaccharides at present, it also was corroborated in disciplinary category analysis.Conclusion: This study revealed the multidimensional field of research on ginseng polysaccharides. Current hot research directions encompassed structural analysis and pharmacological activities in this field, with research hotspots focused on exploring the pharmacological activities of ginseng polysaccharides in gut microbiota and oxidative stress.Keywords: ginseng polysaccharides, bibliometrics, visualization, gut microbiota, oxidative stress