Comparative Efficacy of Endoscopic Lesion Resection and Posterior Lesion Debridement, Bone Grafting, Fusion and Internal Fixation Combined With Medication in the Treatment of Lumbar Brucellosis Spondylitis

Alimujiang Yusufu,1,2,&ast; Abuduwupuer Haibier,1,2,&ast; Yuan Ma1 1Department of Spine Surgery, The Sixth Affiliated Hospital of Xinjiang Medical University, Orthopaedic Hospital of Xinjiang Uygur Autonomous Region, Urumqi, People’s Republic of China; 2Xinjiang Medical University, Xinjiang Uygur Autonomous Region, Urumqi, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Yuan Ma, Email [email protected]: This study intends to compare the efficacy and safety of endoscopic lumbar brucellosis with traditional posterior focus debridement, bone grafting, fusion and internal fixation combined with drugs in the treatment of lumbar brucellosis, and summarize the advantages and disadvantages of different surgical methods, in order to provide theoretical support for clinical surgical decision-making.Methods: The data of 41 lumbar brucellosis patients admitted to the Department of spinal Surgery of the Sixth Affiliated Hospital of Xinjiang Medical University from January 2018 to June 2023 were divided into endoscopic group (Group A, n = 15) and open surgery group (Group B, n = 26). Two groups of general data, surgical and related indicators, blood biochemical and imaging indicators were recorded and analyzed, and the clinical recovery and complications were evaluated according to various scores.Results: There was no statistical difference in baseline data between Group A and Group B, and it could be compared between the two groups; the postoperative lumbar VAS score and hemoglobin index of Group A were significantly better than that of Group B, and the difference was statistically significant (P< 0.05); Group A was significantly better than Group B in terms of operation time, intraoperative blood loss and postoperative time to go down, and the difference was statistically significant (P< 0.05); there was no significant difference between the two groups in other indicators (P> 0.05).Conclusion: The two types of lumbar brucellosis treatment are safe and effective, and the clinical effect of endoscopic surgery is outstanding, which is more conducive to the postoperative rehabilitation of patients. It is recommended when conditions permit.Keywords: lumbar brucellosis spondylitis, LBS, lumbar, lesion removal, endoscopic, posterior surgery