CHANGES IN THE BIOSYNTHETIC ACTIVITY OF STREPTOMYCETES IN THE SOILS OF MOLDOVA GROWN ON MEDIA OF DIFFERENT COMPOSITION

The ability of streptomycete strains isolated from the soils of Moldova to accumulate lipids and amino acids in biomass, depending on the composition of the nutrient medium, was studied. It was found that the studied strains grow better on complex media; of the tested strains, the most biomass (≈20 g) is formed by the Streptomyces gougerotii CNMN-Ac-14 (66) strain on M-1 medium; the maximum amount of lipids (≈13.5%) was found in the strain Streptomyces sp. 49 during growth on M-1 medium, the phospholipid fraction (≈17.2%) was contained in the maximum quantity in the biomass of the strain Streptomyces sp. 49 when growing on R medium, the sterol fraction (≈15%) – in the Streptomyces gougerotii CNMN-Ac-14 (66) strain when growing on M-1 medium. The study of amino acid composition showed that the studied strains synthesize 18-19 amino acids, the total amount of essential amino acids is 35-40%. Keywords: Streptomyces, nutrient medium, biomass, lipids, amino acids. DOI: https://doi.org/10.59295/sum1(181)2025_19