Analysis of Characteristics and Prognostic Factors of Full-Frequency Idiopathic Sudden Sensorineural Hearing Loss with Hyperlipidemia

Feng Qin,1,2 Mingxing Wang,1,2 Jibing Qiu,1,2 Jinbao Guo1,2 1The Changzhou Clinical College of Xuzhou Medical University, Changzhou, Jiangsu, People’s Republic of China; 2Department of Otorhinolaryngology, Changzhou Third People’s Hospital, Changzhou, Jiangsu, People’s Republic of ChinaCorrespondence: Jinbao Guo, Department of Otorhinolaryngology, Changzhou Third People’s Hospital, 300 Lanling North Road, Changzhou, Jiangsu, People’s Republic of China, 213000, Email [email protected]: To explore the relationship between hyperlipidemia and full-frequency idiopathic sudden sensorineural hearing loss (FFHL).Patients and Methods: A total of 145 FFHL patients admitted from September 2021 to May 2024 were analyzed. Eighty-five patients with hyperlipidemia and 60 patients with normal serum lipids statistically analyze the patient’s gender, age, onset time, accompanying symptoms, and serum lipids. Measure the pure tone hearing threshold before and after treatment, and calculate the average increase in hearing threshold. Compare the correlation between various factors and prognosis.Results: The hyperlipidemia group had a higher proportion of males (P=0.043) and vertigo (P=0.044) compared to the control group, while other information between the two groups lacked statistical significance. Effective patients (n=44) in the hyperlipidemia group showed significant differences in vertigo (P=0.020), age (P=0.032), and onset (P=0.030) compared to ineffective patients (n=41). Analysis showed that these were independent correlated factors affecting prognosis. Other indicators, including serum lipids, have no significance in predicting the prognosis of patients with hyperlipidemia and complete frequency decline in hearing loss.Conclusion: Patients with hyperlipidemia have higher rates of males and vertigo. The age, onset, and vertigo of patients with hyperlipidemia are related to prognosis, while various lipid indicators are not related to the prognosis of sudden hearing loss.Keywords: hyperlipidemia, idiopathic sudden sensorineural hearing loss, full frequency hearing loss