Estimation of Residues of Tetracycline and Ciprofloxacin in Hospital Wastewater

The research included estimating the residues of the antibiotics tetracycline and ciprofloxacin in the wastewater of some hospitals. Samples were taken, one sample from each hospital, and these antibiotics were extracted using solid phase extraction methods and then determined using high-performance liquid chromatography technology, with a fluorescence detector, Em = 420, Ex = 310, a C18 column, 25 cm, 4.6 mm, and a mobile phase, Methanol: Dw70:30, for tetracycline, and for ciprofloxacin, a C18 column, 25 cm, 4.6 mm. and 3.5µm with a wavelength of 278nm and a mobile phase of phosphoric acid, acetonitrile and methanol in ratios of 40:40:20, respectively. It was noted that there are significant concentrations of the studied antibiotics, with tetracycline concentrations ranging from 201.1 - 142.5 ppm and ciprofloxacin concentrations from 156.98 - 78.99 ppm. Therefore, it is necessary to monitor these concentrations leaking into the water as long as they affect the environment and human and animal health.

Publication Details

Journal
Umsida Repository (Universitas Muhammadiyah Sidoarjo)
Published
2024-09-01
Primary Topic
Aquatic Invertebrate Ecology and Behavior
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article
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article

Estimation of Residues of Tetracycline and Ciprofloxacin in Hospital Wastewater

Umsida Repository (Universitas Muhammadiyah Sidoarjo)
Aquatic Invertebrate Ecology and Behavior
article

Estimation of Residues of Tetracycline and Ciprofloxacin in Hospital Wastewater

article en

Abstract

The research included estimating the residues of the antibiotics tetracycline and ciprofloxacin in the wastewater of some hospitals. Samples were taken, one sample from each hospital, and these antibiotics were extracted using solid phase extraction methods and then determined using high-performance liquid chromatography technology, with a fluorescence detector, Em = 420, Ex = 310, a C18 column, 25 cm, 4.6 mm, and a mobile phase, Methanol: Dw70:30, for tetracycline, and for ciprofloxacin, a C18 column, 25 cm, 4.6 mm. and 3.5µm with a wavelength of 278nm and a mobile phase of phosphoric acid, acetonitrile and methanol in ratios of 40:40:20, respectively. It was noted that there are significant concentrations of the studied antibiotics, with tetracycline concentrations ranging from 201.1 - 142.5 ppm and ciprofloxacin concentrations from 156.98 - 78.99 ppm. Therefore, it is necessary to monitor these concentrations leaking into the water as long as they affect the environment and human and animal health.

Umsida Repository (Universitas Muhammadiyah Sidoarjo)
Clean water and sanitation
Openalex Percentile: Top 39%
Aquatic Invertebrate Ecology and Behavior
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