A Cohort Study Examining the Risk of Smoking on the Likelihood of Developing Angina Among Women Under Age 65

Objective: To determine if current smoking status is a risk factor for angina among women under the age of 65. Methods: A subset of participants from the Framingham Heart Studywere used to complete a cohort study. The analyses evaluated population means and characteristics, followed by bivariate and multivariable logistic regression, to determine the association of smoking and other key factors with angina. Results: Smoking status had a significant association to angina(OR 0.67, 95% CI: 0.52, 0.86, p-value= 0.0015). Age as a categorical variable had a significant relationship with angina (OR 0.97, 95% CI: 0.617, 1.520, p-value= Conclusions: Smoking had a significant association with occurrences of angina, but the association became nonsignificant after additional control variables were added into the model.