Atatürk Barajı Gölü'ndeki sazanların (Cyprinus carpio L.) iyon homeostazisi ve ozmoregülasyonunda rol oynayan enzimler üzerine kirliliğin etkisi

The Atatürk Dam Lake has recently become the focus of toxicological research due to the fact that it is the largest dam in Türkiye (i); that it is affected by pollutants originating from the intensive activities in the residential areas around the dam (ii); that it contains aquatic products with high economic, commercial and nutritional value (iii); and that undesirable changes in water quality and/or fish have the potential to affect humans (iv). In the current work, changes in the Na+/K+-ATPase (EC 3.6.3.9), Ca2+-ATPase (EC 3.6.3.8) and Mg2+-ATPase (EC 3.6.3.2) activities in the tissues of carps (Cyprinus carpio) caught in Samsat (relatively clean area) and Sitilce (area affected by urban activities) in the Adıyaman province borders and Bozova (area affected by agricultural activities) in the Şanlıurfa province borders of the dam lake in september 2021 were determined. When the Samsat region was compared, significant decreases were observed in all ATPase enzyme activities examined in gill, liver, intestine and kidney tissues of fish from Sitilce and Bozova regions, while enzyme activities in muscle tissue did not show any significant change. Our study clearly demonstrated that the pollutants in the Atatürk Dam Lake have toxic effects on ion balance, ion homeostasis and osmoregulation mechanisms in fish and that ATPases can be used as useful biomarkers in determining pollution in aquatic ecosystems.