ANALYSIS OF CLINICAL AND FUNCTIONAL STATUS IN PATIENTS WITH CHRONIC HEART FAILURE FOLLOWING COVID-19 INFECTION

Objective. This study aimed to analyze echocardiographic, hemodynamic, and functional changes in patients with chronic heart failure (CHF) who had recovered from COVID-19 compared to those who had not. Additionally, we assessed clinical status, quality of life, and key factors influencing disease progression and treatment outcomes.Materials and Methods. A total of 103 patients aged over 60 with CHF were enrolled in the study. Based on medical history, they were divided into two groups: Group 1(n=52): CHF patients with a history of COVID-19 infection. Group 2(n=51): CHF patients without prior COVID-19 infection. The study was conducted at City Clinical Hospital No. 7 in Tashkent. Patients were monitored for one year, with assessments including: Echocardiography (ECHO)for evaluation of left ventricular systolic and diastolic function, ejection fraction (EF), total systolic volume (TSV), and total diastolic volume (TDV). Hemodynamic assessmentwith measurement of systolic blood pressure (SBP) and diastolic blood pressure (DBP).6-minute walk test (6MWT)for exercise tolerance. Blood testsfor analysis of lipid profile and glucose levels. Clinical observations, including frequency of outpatient visits, hospitalizations, and mortality rates. Statistical analysis was performed, with a significance level of p<0.05 considered statistically significant.