Assessing the Molecular Conservation of the Gene Mipp2 Across Drosophila Species

The primary objective of this project is to assess the molecular and structural conservation of Mipp2 within the insulin signaling pathway, across various Drosophila species. We mapped the location of Mipp2 in D. arizonae and annotated its coding sequences. The annotation displayed poor conservation of Mipp2 between D. melanogaster and D. arizonae, showing divergence in all coding exons. We have since annotated Mipp2 across additional Drosophila species and have found that more closely related species exhibit higher conservation of the gene region and the protein coding sequence.