Synthesis of 2,4,5- Triarylimidazol by Using Catalysts under Mild Conditions

This research involves the synthesis of compounds (1-7) of 2,4,5-triarylimidazol by using catalysts under mild conditions. Benzil was reacted with various aromatic aldehyde and ammonium acetate in ethanol in the presence of concentrated sulfuric acid and 8-hydroxy-7-iodoquinoline-5-sulfonic acid (HISA) as catalysts to yield 2,4,5-triarylimidazole derivatives. Among the two catalysts, HISA is an excellent catalyst in the reaction. The reaction conditions are mild and work-up method is simple as well as high yields. The prepared compounds were verified by melting points and were uncorrected and FT-IR spectra.