Short-Term Intermittent Normobaric Hypoxia Combined with Light Exercise Improves Acclimatization of Cardiorespiratory Function in Inactive Adults

Khalid S Aljaloud Department of Exercise Physiology, College of Sport Sciences and Physical Activity, King Saud University, Riyadh, Saudi ArabiaCorrespondence: Khalid S Aljaloud, Department of Exercise Physiology, College of Sport Sciences and Physical Activity, King Saud University, P O Box 2454, Riyadh, Saudi Arabia, Tel +966-8063100, Email [email protected]: Un-acclimatized individuals may experience acute altitude illness. Thus, the current study investigated the impact of short-term intermittent normobaric hypoxia (NH) combined with light exercise on the acclimatization of cardiorespiratory function to altitude in inactive adults.Methods: This quasi-experimental study recruited 10 inactive university students (age: 26.3 ± 2.53 years). All participants were instructed to perform light exercise while exposed to intermittent NH (15%) (2 h/d) for 2 weeks continuously. The heart rate (HR), relative oxygen consumption (VO2 mL/kg/min), minute ventilation (VE), VO2/HR, and respiratory frequency (RF) were measured.Results: Results illustrated a significant improvement in participants’ cardiorespiratory functions by 10 days after exposure to NH, as compared to day 1 of exposure, based on their HR, RF, and VE responses at rest and HR, RF, VE, VO2, VO2/kg, and VO2/HR during light exercise. Resting-state values had returned to the pre-NH exposure levels after 10 days of intermittent NH exposure. Furthermore, values measured during light exercise were significantly decreased on days 10 and 14 as compared to day 1 of NH exposure.Conclusion: This study concluded that as few as 10 days of exposure to intermittent NH (pO2 = 15%) combined with light exercise may improve the acclimation to NH of 15% pO2 in inactive adults.Keywords: altitude, acclamation, oxygen consumption, health-related fitness, training, sedentary