Hepatic Angiosarcoma with eosinophilia: A Case Report and Literature Review

Meiqin Chen,1 Xiguo Chen,2 Shun Wang,1 Dan Lei,1 Chunxian Peng1 1Department of Infectious Diseases, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, People’s Hospital, Quzhou, People’s Republic of China; 2Department of Electromechanical Engineering, Quzhou College of Technology, Quzhou, People’s Republic of ChinaCorrespondence: Chunxian Peng, Email [email protected]: Hepatic angiosarcoma is an extremely rare, uncontrollable tumor with strong invasion, high mortality rate, and extremely poor prognosis. There is first report on hepatic angiosarcoma accompanied by eosinophilia.Case Presentation: A woman with a chief complaint of poor appetite for about 3 months presented to a local hospital with a liver mass. Laboratory examination revealed a significant increase in eosinophils count was 9.58% in the serum. Abdominal MRI revealed multiple focal high-density lesions in the liver and spleen, and cranial MRI revealed multiple high-density shadows in the skull. Laparoscopic biopsy revealed a hepatic angiosarcoma and targeted treatment with Anlotinib was performed. Two months later, the patient died of splenic rupture and bleeding.Conclusion: Hepatic angiosarcoma often has no specific clinical manifestations, and we found that this case can lead to an increase in eosinophils, which is worth the attention of clinical physicians.Keywords: hepatic angiosarcoma, eosinophilia, prognosis, diagnosis, case report